Regulating the gaps between folds on the surface of silk fibroin membranes via LBL deposition for improving their biomedical properties

Silk fibroin (SF) has become a promising biomaterial in guided bone regeneration (GBR). In an attempt to modify the size of the gaps on the surface of SF barrier membrane and improve its antibacterial activity, biological and mechanical properties, positively charged Lysozyme (LY)-Collagen Type-I (COL) composites and negatively charged SF were introduced to the negatively charged surface of SF substrates utilizing the electrostatic...