Technical Note: Insertion of digital lesions in the projection domain for dual-source, dual-energy CT

To compare algorithms performing material decomposition and classification in dual-energy CT, it is desirable to know the ground truth of the lesion to be analyzed in real patient data. In this work, we developed and validated a framework to insert digital lesions of arbitrary chemical composition into patient projection data acquired on a dual-source, dual-energy CT system.A model that takes into account beam-hardening effects was developed to...