Review paper
Evolution of complexity in the zebrafish synapse proteome
Abstract
The proteome of human brain synapses is highly complex and is mutated in over 130 diseases. This complexity arose from two whole-genome duplications early in the vertebrate lineage. Zebrafish are used in modelling human diseases; however, its synapse proteome is uncharacterized, and whether the teleost-specific genome duplication (TSGD) influenced complexity is unknown. We report the characterization of the proteomes and ultrastructure of...
Paper Details
Title
Evolution of complexity in the zebrafish synapse proteome
Published Date
Mar 2, 2017
Journal
Volume
8
Issue
1
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