Original paper

Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake

Volume: 7, Issue: 3, Pages: 353 - 360
Published: May 1, 2017
Abstract
Huperzine A (Hup-A) is a poorly water-soluble drug with low oral bioavailability. A self-microemulsifying drug delivery system (SMEDDS) was used to enhance the oral bioavailability and lymphatic uptake and transport of Hup-A. A single-pass intestinal perfusion (SPIP) technique and a chylomicron flow-blocking approach were used to study its intestinal absorption, mesenteric lymph node distribution and intestinal lymphatic uptake. The value of the...
Paper Details
Title
Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake
Published Date
May 1, 2017
Volume
7
Issue
3
Pages
353 - 360
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.