Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation
Abstract
A wide array of cell signaling mediators and their interactions play vital roles in neuroinflammation associated with ischemia, brain trauma, developmental disorders and age-related neurodegeneration. Along with neurons, microglia and astrocytes are also affected by the inflammatory cascade by releasing pro-inflammatory cytokines, chemokines and reactive oxygen species. The release of pro-inflammatory mediators in response to neural dysfunction...
Paper Details
Title
Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation
Published Date
Jul 1, 2017
Journal
Volume
36
Pages
11 - 19
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Notes
History