Characterization of ferroptosis in murine models of hemochromatosis.

Volume: 66, Issue: 2, Pages: 449 - 465
Published: Aug 1, 2017
Abstract
Ferroptosis is a recently identified iron-dependent form of nonapoptotic cell death implicated in brain, kidney, and heart pathology. However, the biological roles of iron and iron metabolism in ferroptosis remain poorly understood. Here, we studied the functional role of iron and iron metabolism in the pathogenesis of ferroptosis. We found that ferric citrate potently induces ferroptosis in murine primary hepatocytes and bone marrow–derived...
Paper Details
Title
Characterization of ferroptosis in murine models of hemochromatosis.
Published Date
Aug 1, 2017
Journal
Volume
66
Issue
2
Pages
449 - 465
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