Structural Analysis of Chemokine Receptor–Ligand Interactions
Abstract
This review focuses on the construction and application of structural chemokine receptor models for the elucidation of molecular determinants of chemokine receptor modulation and the structure-based discovery and design of chemokine receptor ligands. A comparative analysis of ligand binding pockets in chemokine receptors is presented, including a detailed description of the CXCR4, CCR2, CCR5, CCR9, and US28 X-ray structures, and their...
Paper Details
Title
Structural Analysis of Chemokine Receptor–Ligand Interactions
Published Date
Mar 10, 2017
Volume
60
Issue
12
Pages
4735 - 4779
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