Radiation Induced CD8 T-Lymphocyte Apoptosis as a Predictor of Late Toxicity After Radiation Therapy: Results of the Prospective Multicenter French Trial

Purpose/Objective(s)We showed in retrospective and monocentric studies that radiation-induced CD8-lymphocyte apoptosis (RILA) can significantly predict differences in late toxicity between individuals and can be used as a rapid screening for potential hyperreactive patients to radiation therapy (RT). Here, we presented the clinical results of the prospective multicenter French trial (NCT00893035) evaluating the role of RILA as a predictor of...