Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias
Abstract
The parasympathetic nervous system plays an important role in the pathophysiology of atrial fibrillation. Catheter ablation, a minimally invasive procedure deactivating abnormal firing cardiac tissue, is increasingly becoming the therapy of choice for atrial fibrillation. This is inevitably associated with the obliteration of cardiac cholinergic neurons. However, the impact on ventricular electrophysiology is unclear. Here we show that cardiac...
Paper Details
Title
Disruption of cardiac cholinergic neurons enhances susceptibility to ventricular arrhythmias
Published Date
Jan 27, 2017
Journal
Volume
8
Issue
1
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