miR-668 enhances the radioresistance of human breast cancer cell by targeting IκBα

Volume: 24, Issue: 5, Pages: 673 - 682
Published: Jan 30, 2017
Abstract
A large proportion of breast cancer patients are resistant to radiotherapy, which is a mainstay treatment for this malignancy, but the mechanisms of radioresistance remain unclear. To evaluate the role of miRNAs in radioresistance, we established two radioresistant breast cancer cell lines MCF-7R and T-47DR derived from parental MCF-7 and T-47D. Moreover, miRNA microarray, quantitative RT-PCR analysis, luciferase reporter assay and western...
Paper Details
Title
miR-668 enhances the radioresistance of human breast cancer cell by targeting IκBα
Published Date
Jan 30, 2017
Volume
24
Issue
5
Pages
673 - 682
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