Re: Rational and irrational ratios

In his Opinion paper, Cuckle describes the use of ratios in different screening protocols in maternal-fetal medicine. The paper is both very educative, including historical information about the genesis of biomarker screening, and well-written. However, there is one major flaw. We do not agree with the following sentence: ‘This brief review of ratios in prenatal screening shows that only one type, MoM [multiples of the median], has obvious...