Visceral and somatic pain modalities reveal NaV1.7‐independent visceral nociceptive pathways
Abstract
Key points Voltage‐gated sodium channels play a fundamental role in determining neuronal excitability. Specifically, voltage‐gated sodium channel subtype Na V 1.7 is required for sensing acute and inflammatory somatic pain in mice and humans but its significance in pain originating from the viscera is unknown. Using comparative behavioural models evoking somatic and visceral pain pathways, we identify the requirement for Na V 1.7 in regulating...
Paper Details
Title
Visceral and somatic pain modalities reveal NaV1.7‐independent visceral nociceptive pathways
Published Date
Mar 1, 2017
Journal
Volume
595
Issue
8
Pages
2661 - 2679
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