Cerebrospinal fluid levels of orexin-A and histamine, and sleep profile within the Alzheimer process
Abstract
To better understand how sleep/wake dysregulation affects Alzheimer's disease (AD), we compared the cerebrospinal fluid (CSF) orexin and histamine/tele-methylhistamine (HA/t-MHA) levels of 82 patients (41 probable-AD-high level of evidence, 41 mild cognitive impairment MCI-due-to-AD), 24 other neurologic disorders (OND) and 24 controls. We determined the relationships between these biomarkers, the CSF AD biomarkers concentrations, and the...
Paper Details
Title
Cerebrospinal fluid levels of orexin-A and histamine, and sleep profile within the Alzheimer process
Published Date
May 1, 2017
Journal
Volume
53
Pages
59 - 66
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History