Systematic characterization of Pluronic® micelles and their application for solubilization and in vitro release of some hydrophobic anticancer drugs

The utilization of polymeric micelles in oncology in the last few decades has progressed by leaps and bounds from the advances in polymer chemistry, in drug formulation and delivery (in vitro and in vivo biological models). Commercially available linear (A-B-A type) ethylene oxide-propylene oxide (EO-PO) block copolymers, Pluronics® have acquired added attention by virtue of their capability to load therapeutics, execute the delivery of the...