In silico enhancement of the stability and activity of keratinocyte growth factor
Abstract
Keratinocyte growth factor (KGF), a member of the fibroblast growth factor (FGF) family, has been implicated in some biological processes such as cell proliferation, development and differentiation. High mitogenic activity of this protein has made it very suitable for repairing radiation-and chemotherapy-induced damages. Palifermin, which has been developed from human KGF, is clinically applied to reduce the incidence and duration of cancer...
Paper Details
Title
In silico enhancement of the stability and activity of keratinocyte growth factor
Published Date
Apr 1, 2017
Volume
418
Pages
111 - 121
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