Triphenylphosphonium cations of betulinic acid derivatives: synthesis and antitumor activity
Abstract
A series of lupane triterpenoid conjugates with the triphenylphosphonium cation, in which the terpenoid molecules are linked to one or two triphenylphosphonium moieties at the С-2, С-28, or С-30 positions by carbon–carbon or ester bonds, have been designed and synthesized as potential anti-cancer agents. The pharmacological results showed that all of the prepared triphenylphosphonium salts displayed considerable antitumor activities against the...
Paper Details
Title
Triphenylphosphonium cations of betulinic acid derivatives: synthesis and antitumor activity
Published Date
Jan 5, 2017
Journal
Volume
26
Issue
3
Pages
518 - 531
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