Polycomb complexes PRC1 and their function in hematopoiesis
Abstract
Hematopoiesis, the process by which blood cells are continuously produced, is one of the best studied differentiation pathways. Hematological diseases are associated with reiterated mutations in genes encoding important gene expression regulators, including chromatin regulators. Among them, the Polycomb group (PcG) of proteins is an essential system of gene silencing involved in the maintenance of cell identities during differentiation. PcG...
Paper Details
Title
Polycomb complexes PRC1 and their function in hematopoiesis
Published Date
Apr 1, 2017
Journal
Volume
48
Pages
12 - 31
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