Ferroptosis and cell death mechanisms in Parkinson's disease.
Abstract
Symptoms of Parkinson's disease arise due to neuronal loss in multiple brain regions, especially dopaminergic neurons in the substantia nigra pars compacta. Current therapies aim to restore dopamine levels in the brain, but while these provide symptomatic benefit, they do not prevent ongoing neurodegeneration. Preventing neuronal death is a major strategy for disease-modifying therapies; however, while many pathogenic factors have been...
Paper Details
Title
Ferroptosis and cell death mechanisms in Parkinson's disease.
Published Date
Mar 1, 2017
Journal
Volume
104
Pages
34 - 48
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Notes
History