Role of induction chemotherapy in the multimodal management of locally advanced epithelial sinonasal cancer

Background: Outcomes of locally advanced epithelial sinonasal cancer remain unsatisfactory, despite the improvement in surgical approaches and advances in radiotherapy techniques. The incorporation of induction chemotherapy (IC) in the multimodal treatment strategy has shown promising results in few studies. Only limited and heterogeneous data exist on prognostic factors, due to the rarity of this disease. Material and methods: We reviewed...