LCN2 overexpression in bone enhances the hematopoietic compartment via modulation of the bone marrow microenvironment

Lipocalin‐2 (LCN2) is a member of the lipocalin family whose expression is modulated in several conditions, including cell differentiation, innate immunity, stress, and cancer. Although it is known that it is expressed in bone, its function in this tissue remains poorly studied. To this end, we took advantage of transgenic mice lines that expressed LCN2 driven by a bone specific type I collagen (LCN2‐Tg). In the bone marrow (BM) of LCN2‐Tg mice...