PD-1 blockade modulates chimeric antigen receptor (CAR)–modified T cells: refueling the CAR
Abstract
To the editor:
Antibodies blocking the programmed death 1 receptor (PD-1) on T cells produce tumor regression in multiple cancers by disrupting the PD-L1/PD-1 (programmed death-ligand 1/programmed cell death protein 1) immune inhibitory axis.[1][1][⇓][2][⇓][3][⇓][4]-[5][5] This approach...
Paper Details
Title
PD-1 blockade modulates chimeric antigen receptor (CAR)–modified T cells: refueling the CAR
Published Date
Feb 23, 2017
Journal
Volume
129
Issue
8
Pages
1039 - 1041
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Notes
History