Interplay of extracellular matrix and leukocytes in lung inflammation
Abstract
During inflammation, leukocytes influx into lung compartments and interact with extracellular matrix (ECM). Two ECM components, versican and hyaluronan, increase in a range of lung diseases. The interaction of leukocytes with these ECM components controls leukocyte retention and accumulation, proliferation, migration, differentiation, and activation as part of the inflammatory phase of lung disease. In addition, bronchial epithelial cells from...
Paper Details
Title
Interplay of extracellular matrix and leukocytes in lung inflammation
Published Date
Feb 1, 2017
Journal
Volume
312
Pages
1 - 14
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