Doxorubicin enhances the capacity of B cells to activate T cells in urothelial urinary bladder cancer
Abstract
Cancer is currently treated by a combination of therapies, including chemotherapy which is believed to suppress the immune system. Combination of immunotherapy and chemotherapy correlates with improved survival but needs careful planning in order to achieve a synergistic effect. In this study, we have demonstrated that doxorubicin treatment of B cells resulted in increased expression of CD86 and concordantly increased CD4+ T cell activation in...
Paper Details
Title
Doxorubicin enhances the capacity of B cells to activate T cells in urothelial urinary bladder cancer
Published Date
Mar 1, 2017
Journal
Volume
176
Pages
63 - 70
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Notes
History