Natural deep eutectic solvents and ultrasound-assisted extraction: Green approaches for extraction of wine lees anthocyanins

To establish environmentally friendly extraction methods for the anthocyanins in wine lees, natural deep eutectic solvents (NADES) were investigated as a green alternative to conventional solvents, coupled with high-efficiency ultrasound-assisted extraction. Screening for the optimal NADES for this extraction was initially performed. A choline–chloride-based NADES with malic acid as the hydrogen bond donor was selected as the most promising,...