Abstract 2239: The tumor stem cell marker doublecortin-like kinase (DCLK1) activates inflammatory and carcinogenic signals in hepatocellular carcinoma

Introduction: Hepatocellular Carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide. Chronic viral hepatitis, non-alcoholic steatohepatitis and cirrhosis are considered to be major risk factors for the development of HCC. The risk of HCC increases significantly in patients with chronic hepatitis C virus (HCV) infection and metabolic diseases. Thus, HCC represents a wide-ranging public health issue worldwide. Our recent...