Identification of novel loci affecting circulating chromogranins and related peptides
Abstract
Chromogranins are pro-hormone secretory proteins released from neuroendocrine cells, with effects on control of blood pressure. We conducted a genome-wide association study for plasma catestatin, the catecholamine release inhibitory peptide derived from chromogranin A (CHGA), and other CHGA- or chromogranin B (CHGB)-related peptides, in 545 US and 1252 Australian subjects. This identified loci on chromosomes 4q35 and 5q34 affecting catestatin...
Paper Details
Title
Identification of novel loci affecting circulating chromogranins and related peptides
Published Date
Dec 22, 2016
Journal
Pages
ddw380 - ddw380
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