Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury
Abstract
Oxidative stress plays a major role in acute and chronic liver injury. In hepatocytes, oxidative stress frequently triggers antioxidant response by activating nuclear erythroid 2-related factor 2 (Nrf2), a transcription factor, which upregulates various cytoprotective genes. Thus, Nrf2 is considered a potential therapeutic target to halt liver injury. Several studies indicate that activation of Nrf2 signaling pathway ameliorates liver injury....
Paper Details
Title
Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury
Published Date
Jan 1, 2016
Volume
2016
Pages
1 - 13
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