Allopurinol as a therapeutic option in cardiovascular disease
Volume: 172, Pages: 139 - 150
Published: Apr 1, 2017
Abstract
Epidemiological studies indicate that hyperuricaemia is an independent risk factor for cardiovascular disease. Alongside uric acid formation, increased xanthine oxidase activity also results in the formation of oxidative free radicals and superoxide particles. Oxidative stress significantly contributes to the development of cardiovascular disease, including endothelial cell dysfunction, atherosclerosis, vascular calcification and impaired...
Paper Details
Title
Allopurinol as a therapeutic option in cardiovascular disease
Published Date
Apr 1, 2017
Volume
172
Pages
139 - 150
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