Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence
Abstract
It has previously been shown that the inhibition of L-type calcium channels (LTCCs) decreases alcohol consumption, although the contribution of the central LTCC subtypes Cav1.2 and Cav1.3 remains unknown. Here, we determined changes in Cav1.2 (Cacna1c) and Cav1.3 (Cacna1d) mRNA and protein expression in alcohol-dependent rats during protracted abstinence and naive controls using in situ hybridization and western blot analysis. Functional...
Paper Details
Title
Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence
Published Date
Dec 1, 2016
Journal
Volume
42
Issue
5
Pages
1058 - 1069
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