The cumulative effect of frailty and cognition on mortality – results of a prospective cohort study

Both physical frailty and cognitive impairment predict death, but the joint effect of these two factors is uncertain. The objectives are to determine if the Mini-mental state examination (MMSE) and the Frailty Index (FI) predict death over a five-year interval after accounting for the effect of the other; and if there is an interaction in this effect.An analysis of an existing prospective cohort study of 1,751 community living older adults...