Localized Mechanical Stress Promotes Microtubule Rescue
Abstract
Microtubule dynamics rely on the properties of tubulin and are regulated by microtubule-associated proteins. GTP-tubulin assembles into hollow polymers, which can depolymerize upon GTP hydrolysis. Depolymerizing microtubules may stop shrinking and resume growth. Such rescues are regulated by microtubule-associated proteins like CLIP-170 and the CLASPs [1Komarova Y.A. Akhmanova A.S. Kojima S. Galjart N. Borisy G.G. Cytoplasmic linker proteins...
Paper Details
Title
Localized Mechanical Stress Promotes Microtubule Rescue
Published Date
Dec 1, 2016
Journal
Volume
26
Issue
24
Pages
3399 - 3406
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History