Clinical Translation of Tumor Acidosis Measurements with AcidoCEST MRI

Volume: 19, Issue: 4, Pages: 617 - 625
Published: Aug 1, 2017
Abstract
We optimized acido-chemical exchange saturation transfer (acidoCEST) magnetic resonance imaging (MRI), a method that measures extracellular pH (pHe), and translated this method to the radiology clinic to evaluate tumor acidosis. A CEST-FISP MRI protocol was used to image a flank SKOV3 tumor model. Bloch fitting modified to include the direct estimation of pH was developed to generate parametric maps of tumor pHe in the SKOV3 tumor model, a...
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Paper Details
Title
Clinical Translation of Tumor Acidosis Measurements with AcidoCEST MRI
Published Date
Aug 1, 2017
Volume
19
Issue
4
Pages
617 - 625
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