Argon reduces the ET-1 induced increase of segmental PVR and the generation of lung edema

Introduction: Argon exerts neuroprotection [1] and might improve the outcome of patients after cardiopulmonary resuscitation, intracerebral bleeding or traumatic brain injury. In patients suffering from left heart disease (LHD) and pulmonary hypertension (PH), limited data for the effect of argon on the pulmonary vascular resistance (PVR) are available. Recently, Neyrinck et al. showed that argon does not alter total PVR in pigs. Aims...