Metabolomic biomarkers predictive of early structural lung disease in cystic fibrosis
Abstract
Neutrophilic airway inflammation plays a role in early structural lung disease in cystic fibrosis, but the mechanisms underlying this pathway are incompletely understood.Metabolites associated with neutrophilic inflammation were identified by discovery metabolomics on bronchoalveolar lavage fluid supernatant from 20 preschool children (2.9±1.3 years) with cystic fibrosis. Targeted mass-spectrometric detection of relevant metabolites was then...
Paper Details
Title
Metabolomic biomarkers predictive of early structural lung disease in cystic fibrosis
Published Date
Nov 11, 2016
Journal
Volume
48
Issue
6
Pages
1612 - 1621
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