The effect of IDH1 mutation on the structural connectome in malignant astrocytoma

Volume: 131, Issue: 3, Pages: 565 - 574
Published: Nov 15, 2016
Abstract
Mutation of the IDH1 gene is associated with differences in malignant astrocytoma growth characteristics that impact phenotypic severity, including cognitive impairment. We previously demonstrated greater cognitive impairment in patients with IDH1 wild type tumor compared to those with IDH1 mutant, and therefore we hypothesized that brain network organization would be lower in patients with wild type tumors. Volumetric, T1-weighted MRI scans...
Paper Details
Title
The effect of IDH1 mutation on the structural connectome in malignant astrocytoma
Published Date
Nov 15, 2016
Volume
131
Issue
3
Pages
565 - 574
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