Vasculogenic mimicry in small cell lung cancer.

Volume: 7, Issue: 1, Pages: 13322 - 13322
Published: Nov 9, 2016
Abstract
Small cell lung cancer (SCLC) is characterized by prevalent circulating tumour cells (CTCs), early metastasis and poor prognosis. We show that SCLC patients (37/38) have rare CTC subpopulations co-expressing vascular endothelial-cadherin (VE-cadherin) and cytokeratins consistent with vasculogenic mimicry (VM), a process whereby tumour cells form 'endothelial-like' vessels. Single-cell genomic analysis reveals characteristic SCLC genomic changes...
Paper Details
Title
Vasculogenic mimicry in small cell lung cancer.
Published Date
Nov 9, 2016
Volume
7
Issue
1
Pages
13322 - 13322
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