Tumor control and normal tissue toxicity: The two faces of radiotherapy
Published: Jan 1, 2016
Abstract
This thesis discusses the two contrasting sides of radiotherapy: tumor control and normal tissue toxicity. On one hand, radiation treatment aims to target the tumor with the highest possible radiation dose, inducing as much lethal DNA damage as possible. On the other hand however, escalation of the radiation dose will also result in an increase of normal tissue damage and hence of the normal tissue complication rate. Unfortunately, ionizing...
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