Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis
Abstract
Angiogenesis, the recruitment of new blood vessels, is a critical process for the growth, expansion, and metastatic dissemination of developing tumors. Three types of cells make up the new vasculature: tip cells, which migrate in response to gradients of vascular endothelial growth factor (VEGF), stalk cells, which proliferate and extend the vessels, and phalanx cells, which are quiescent and support the sprout. In this study we examine the...
Paper Details
Title
Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis
Published Date
Nov 14, 2016
Journal
Volume
6
Issue
1
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