Advances in analytical methodologies to guide bioprocess engineering for bio-therapeutics

Volume: 116, Pages: 63 - 83
Published: Mar 1, 2017
Abstract
This study was performed to monitor the glycoform distribution of a recombinant antibody fusion protein expressed in CHO cells over the course of fed-batch bioreactor runs using high-throughput methods to accurately determine the glycosylation status of the cell culture and its product. Three different bioreactors running similar conditions were analysed at the same five time-points using the advanced methods described here. N-glycans from cell...
Paper Details
Title
Advances in analytical methodologies to guide bioprocess engineering for bio-therapeutics
Published Date
Mar 1, 2017
Journal
Volume
116
Pages
63 - 83
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