Reduced PICD in Monocytes Mounts Altered Neonate Immune Response to Candida albicans
Abstract
Background Invasive fungal infections with Candida albicans (C. albicans) occur frequently in extremely low birthweight (ELBW) infants and are associated with poor outcome. Phagocytosis of C.albicans initializes apoptosis in monocytes (phagocytosis induced cell death, PICD). PICD is reduced in neonatal cord blood monocytes (CBMO). Hypothesis Phagocytosis of C. albicans causes PICD which differs between neonatal monocytes (CBMO) and adult...
Paper Details
Title
Reduced PICD in Monocytes Mounts Altered Neonate Immune Response to Candida albicans
Published Date
Nov 21, 2016
Journal
Volume
11
Issue
11
Pages
e0166648 - e0166648
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