3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development
Abstract
No treatments exist to effectively treat many retinal diseases. Retinal pigmented epithelium (RPE) and neural retina can be generated from human embryonic stem cells/induced pluripotent stem cells (hESCs/hiPSCs). The efficacy of current protocols is, however, limited. It was hypothesised that generation of laminated neural retina and/or RPE from hiPSCs/hESCs could be enhanced by three dimensional (3D) culture in hydrogels. hiPSC- and...
Paper Details
Title
3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development
Published Date
Feb 1, 2017
Journal
Volume
49
Pages
329 - 343
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