Specific inhibition of TRPV4 enhances retinal ganglion cell survival in adult porcine retinal explants
Abstract
Signaling through the polymodal cation channel Transient Receptor Potential Vanilloid 4 (TRPV4) has been implicated in retinal neuronal degeneration. To further outline the involvement of this channel in this process, we here explore modulation of Transient Receptor Potential Vanilloid 4 (TRPV4) activity on neuronal health and glial activation in an in vitro model of retinal degeneration. For this purpose, adult porcine retinal explants were...
Paper Details
Title
Specific inhibition of TRPV4 enhances retinal ganglion cell survival in adult porcine retinal explants
Published Date
Jan 1, 2017
Journal
Volume
154
Pages
10 - 21
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