MET/ERK2 pathway regulates the motility of human alveolar rhabdomyosarcoma cells
Abstract
In alveolar rhabdomyosarcoma (ARMS) that is a highly malignant pediatric soft tissue tumor, MET, a receptor of hepatocyte growth factor (HGF), was reported to be downstream of the PAX3-FOXO1 fusion gene specific to ARMS, and a key mediator of metastatic behavior in RMS. So far, no studies have investigated the downstream signaling pathways of MET in ARMS, even though HGF and MET have been suggested to be deeply involved in the invasiveness of...
Paper Details
Title
MET/ERK2 pathway regulates the motility of human alveolar rhabdomyosarcoma cells
Published Date
Nov 2, 2016
Journal
Volume
37
Issue
1
Pages
98 - 104
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