Direct and Practical Synthesis of Primary Anilines through Iron-Catalyzed C–H Bond Amination
Abstract
The direct C–H amination of arenes is an important strategy to streamline the discovery and preparation of functional molecules. Herein, we report an operationally simple arene C–H amination reaction that, in contrast to most literature precedent, affords directly the synthetically versatile primary aniline products without relying on protecting group manipulations. Inexpensive Fe(II)-sulfate serves as a convenient catalyst for the...
Paper Details
Title
Direct and Practical Synthesis of Primary Anilines through Iron-Catalyzed C–H Bond Amination
Published Date
Nov 4, 2016
Journal
Volume
6
Issue
12
Pages
8162 - 8165
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