Fabrication and evaluation of silica-based ceramic scaffolds for hard tissue engineering applications

In recent decades, bone scaffolds have received a great attention in biomedical applications due to their critical roles in bone tissue regeneration, vascularization, and healing process. One of the main challenges of using scaffolds in bone defects is the mechanical strength mismatch between the implant and surrounding host tissue which causes stress shielding or failure of the implant during the course of treatment. In this paper, space holder...