Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
Volume: 213, Issue: 12, Pages: 2745 - 2758
Published: Oct 24, 2016
Abstract
Natural killer (NK) cells provide important host defense and can generate long-lived memory NK cells. Here, by using novel transgenic mice carrying inducible Cre expressed under the control of Ncr1 gene, we demonstrated that two distinct long-lived NK cell subsets differentiate in a mouse model of cytomegalovirus (MCMV) infection. NK cells expressing the MCMV-specific Ly49H receptor differentiated into memory NK cells by an activating signaling...
Paper Details
Title
Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
Published Date
Oct 24, 2016
Volume
213
Issue
12
Pages
2745 - 2758
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