Original paper

A prevalent intraresidue hydrogen bond stabilizes proteins

Volume: 12, Issue: 12, Pages: 1084 - 1088
Published: Oct 17, 2016
Abstract
Current limitations in de novo protein structure prediction and design suggest an incomplete understanding of the interactions that govern protein folding. Here we demonstrate that previously unappreciated hydrogen bonds occur within proteins between the amide proton and carbonyl oxygen of the same residue. Quantum calculations, infrared spectroscopy, and nuclear magnetic resonance spectroscopy show that these interactions share hallmark...
Paper Details
Title
A prevalent intraresidue hydrogen bond stabilizes proteins
Published Date
Oct 17, 2016
Volume
12
Issue
12
Pages
1084 - 1088
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