Heterogeneous cortical atrophy patterns in MCI not captured by conventional diagnostic criteria

We investigated differences in regional cortical thickness between previously identified empirically derived mild cognitive impairment (MCI) subtypes (amnestic MCI, dysnomic MCI, dysexecutive/mixed MCI, and cluster-derived normal) in order to determine whether these cognitive subtypes would show different patterns of cortical atrophy.Participants were 485 individuals diagnosed with MCI and 178 cognitively normal individuals from the Alzheimer's...