Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL—another piece in the puzzle
Abstract
Expression of microRNAs is altered in cancer. Circulating miRNA level assessed in body fluids commonly reflects their expression in tumor cells. In leukemias, however, both leukemic and nonleukemic cells compose circulating miRNA expression profile of peripheral blood. The latter contribution to extracellular miRNA pool may result in specific microenvironmental signaling, which promotes proliferation and survival. In our study, we used qT-PCR to...
Paper Details
Title
Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL—another piece in the puzzle
Published Date
Oct 12, 2016
Journal
Volume
96
Issue
1
Pages
33 - 50
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