The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype

Blood20.30
Volume: 128, Issue: 25, Pages: 2960 - 2975
Published: Dec 22, 2016
Abstract
Key Points Key biological features of MDSs are explained by NLRP3 inflammasome activation, which drives pyroptotic cell death and β-catenin activation. Alarmin signals and founder gene mutations license this redox-sensitive inflammasome...
Paper Details
Title
The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype
Published Date
Dec 22, 2016
Journal
Volume
128
Issue
25
Pages
2960 - 2975
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